Interactor 1: IRS1 (P35568)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1

Interactor 2: TRI72 (Q6ZMU5)
Tripartite motif-containing protein 72 (Mitsugumin-53) (Mg53)
Gene: TRIM72

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.708

The method score is based on:

Property Details
Experiments 27810898, 29884820, 32055715, 36337049
Identification Methods affinity chromatography technology, protein complementation assay, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0046627 - negative regulation of insulin receptor signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1242
Hs

1 477
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024