Interactor 1: IRS1 (P35569)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1

Interactor 2: RAN (P62827)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 15602769
Identification Methods tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019904 - protein domain specific binding
GO:0044877 - protein-containing complex binding
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1233
Mm

1 216
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024