HitPredict

Interactor 1: MYH9 (P35579)
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)
Gene: MYH9

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Myosin_head
Common GO terms	GO:0001725 - stress fiber GO:0005524 - ATP binding GO:0005829 - cytosol GO:0015629 - actin cytoskeleton GO:0043531 - ADP binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1960 Hs			1 377
+	Hs
		724738 MYH9_HUMAN (1-1923): 0: 1124: 100.00		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		724762 MYH9_HUMAN (1-1923): 0: 1124: 100.00		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		724766 MYH9_HUMAN (1-1923): 0: 1124: 100.00		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Dm
		361160 MYSA_DROME (939-1960): 2.45e-65: 248: 17.74		ACT4_DROME (1-377): 0: 622: 91.78
+	Dm
		404232 MYSA_DROME (939-1960): 2.45e-65: 248: 17.74		ACT6_DROME (1-377): 0: 600: 92.57
+	Rn
		892236 MYH10_RAT (943-1959): 2.22e-62: 239: 17.24		ACTB_RAT (5-377): 0: 604: 93.83
+	Mm
		892205 MYH9_MOUSE (954-1960): 2.59e-61: 235: 17.10		ACTB_MOUSE (5-377): 0: 604: 93.83
+	Rn
		892228 MYH9_RAT (1277-1960): 2e-42: 173: 15.32		ACTB_RAT (5-377): 0: 604: 93.83
+	Hs
		725136 MYH10_HUMAN (1676-1957): 4.42e-10: 67.4: 16.84		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		725135 MYH10_HUMAN (1676-1957): 4.42e-10: 67.4: 16.84		ACTH_HUMAN (4-377): 0: 597: 98.40