Interactor 1: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Interactor 2: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 37071682, 21078954
Identification Methods cross-linking study, cosedimentation in solution
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IQ~IQ, IQ~Myosin_head, Myosin_head~Myosin_head, Myosin_N~Myosin_head, Myosin_head~Myosin_tail_1, Myosin_N~Myosin_tail_1, Myosin_tail_1~Myosin_tail_1
Common GO terms GO:0000146 - microfilament motor activity
GO:0000281 - mitotic cytokinesis
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005516 - calmodulin binding
and 23 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1976
Hs

1 1976
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Ce

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Last updated: 15 Jul 2024