HitPredict

Interactor 1: SOAT1 (P35610)
Sterol O-acyltransferase 1 (EC 2.3.1.26) (Acyl-coenzyme A:cholesterol acyltransferase 1) (ACAT-1) (Cholesterol acyltransferase 1)
Gene: SOAT1

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 550 Hs			1 618
+	Hs
		545235 SOAT1_HUMAN (1-550): 0: 811: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		725752 SOAT1_HUMAN (1-550): 0: 811: 100.00		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		725753 SOAT1_HUMAN (1-550): 0: 811: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		725791 SOAT1_HUMAN (1-550): 0: 811: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		725770 SOAT1_HUMAN (1-550): 0: 811: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		725764 SOAT1_HUMAN (1-550): 0: 811: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		725761 SOAT1_HUMAN (1-550): 0: 811: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		725756 SOAT1_HUMAN (1-550): 0: 811: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		725880 SOAT1_HUMAN (1-550): 0: 811: 100.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		436178 SOAT1_HUMAN (1-550): 0: 811: 100.00		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120324 SOAT1_HUMAN (1-550): 0: 811: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89