HitPredict

Interactor 1: ADDB (P35612)
Beta-adducin (Erythrocyte adducin subunit beta)
Gene: ADD2

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005200 - structural constituent of cytoskeleton GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 726 Hs			1 375
+	Hs
		892086 ADDG_HUMAN (1-726): 0: 793: 53.28		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		930038 ADDG_HUMAN (1-726): 0: 793: 53.28		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932428 ADDG_HUMAN (1-726): 0: 793: 53.28		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		725933 ADDA_HUMAN (1-715): 0: 733: 46.07		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		725941 ADDA_HUMAN (1-715): 0: 733: 46.07		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		725944 ADDA_HUMAN (1-715): 0: 733: 46.07		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Dm
		54871 A1ZA72_DROME (390-714): 7.43e-09: 61.6: 10.29		ACT6_DROME (2-375): 0: 594: 95.99