Interactor 1: TIMP3 (P35625)
Metalloproteinase inhibitor 3 (Protein MIG-5) (Tissue inhibitor of metalloproteinases 3) (TIMP-3)
Gene: TIMP3

Interactor 2: ADA17 (P78536)
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b)
Gene: ADAM17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.660

The method score is based on:

Property Details
Experiments 12044879, 33961781, 19666115
Identification Methods pull down, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0046872 - metal ion binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 211
Hs

1 824
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024