HitPredict

Interactor 1: TIMP3 (P35625)
Metalloproteinase inhibitor 3 (Protein MIG-5) (Tissue inhibitor of metalloproteinases 3) (TIMP-3)
Gene: TIMP3

Interactor 2: NELL1 (Q92832)
Protein kinase C-binding protein NELL1 (NEL-like protein 1) (Nel-related protein 1)
Gene: NELL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 810
+	Hs
		344790 TIMP1_HUMAN (6-194): 9.47e-81: 241: 38.97		CO5A1_HUMAN (31-232): 9.57e-54: 204: 23.33
+	Hs
		726528 TIMP3_HUMAN (1-211): 4.11e-121: 343: 100.00		SORL_HUMAN (166-417): 2.1e-15: 83.2: 10.60
+	Hs
		726513 TIMP3_HUMAN (1-211): 4.11e-121: 343: 100.00		NOTC2_HUMAN (151-576): 1.14e-11: 70.8: 11.44
+	Hs
		726525 TIMP3_HUMAN (1-211): 4.11e-121: 343: 100.00		FRAS1_HUMAN (265-751): 1.2e-09: 64.5: 18.12