HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25192599
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 245
+	Hs
		646684 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Mm
		882680 FUS_MOUSE (1-526): 6.91e-34: 136: 86.72		1433E_MOUSE (2-241): 9.9e-144: 403: 68.18
+	Hs
		926939 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Mm
		910257 EWS_MOUSE (3-451): 2.8e-30: 127: 35.56		1433E_MOUSE (2-241): 9.9e-144: 403: 68.18
+	Hs
		927658 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		910157 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		683812 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		927003 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		909516 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		516444 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		646864 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		683319 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		110785 H7BY36_HUMAN (273-447): 1.78e-41: 152: 46.15		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		68796 CO6A5_HUMAN (32-261): 2.79e-09: 62.2: 22.84		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		684249 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Hs
		905260 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		684394 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97
+	Hs
		516440 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		516374 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97