HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.904

The method score is based on:

Property Details
Experiments 24999758, 29884807, 24981860, 21988832, 23975937
Identification Methods proximity labelling technology, affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1
Common GO terms GO:0003712 - transcription coregulator activity
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 2 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 526
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024