HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	29884807, 27460707
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 526 Hs			1 282
+	Hs
		1031411 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		516620 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		516383 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		726795 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		967154 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		925089 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		726730 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		516744 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		726950 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		PPIL4_HUMAN (117-195): 7.73e-27: 110: 39.24
+	Hs
		925008 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		925150 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		1031507 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		516768 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		1031314 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Dm
		90750 E1JI93_DROME (59-284): 4.71e-13: 74.3: 17.70		TRA2_DROME (97-281): 1.36e-44: 153: 43.78
+	Mm
		892749 Q8BQ46_MOUSE (42-460): 2.55e-40: 155: 48.34		CIRBP_MOUSE (121-193): 1.3e-10: 60.8: 58.90
+	Hs
		516495 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		680441 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		TIA1_HUMAN (114-207): 1.64e-18: 86.4: 21.28
+	Mm
		857328 EWS_MOUSE (3-451): 2.8e-30: 127: 35.56		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	At
		97485 TAF15_ARATH (281-452): 1.02e-39: 149: 34.30		SUA_ARATH (117-197): 2.18e-09: 60.2: 37.35