HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28515276, 29884807, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 972
+	Hs
		1064550 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		967184 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064837 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064906 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		212142 HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1031337 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		516526 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		867098 SC24C_HUMAN (1-262): 5.36e-11: 67.4: 14.34		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		531057 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		EF2_HUMAN (111-957): 0: 915: 38.16
+	Hs
		531312 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		EF2_HUMAN (111-957): 0: 915: 38.16
+	Sp
		292934 PABP_SCHPO (242-381): 4.01e-12: 70.8: 15.71		SN114_SCHPO (1-970): 0: 928: 54.22