HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.865

The method score is based on:

Property Details
Experiments 29884807, 35271311, 27731383
Identification Methods affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RRM_1~RRM_1
Common GO terms GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 526
Hs

1 915
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024