HitPredict

Interactor 1: HS104 (P31539)
Heat shock protein 104 (Protein aggregation-remodeling factor HSP104)
Gene: HSP104

Interactor 2: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	36704946, 38182580, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042026 - protein refolding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 908 Sc			1 693
+	Sc
		726864 HS104_YEAST (1-908): 0: 896: 100.00		HSP79_YEAST (1-677): 0: 992: 77.11
+	Sc
		741273 HSP78_YEAST (103-867): 0: 744: 42.53		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Hs
		537875 CLPB_HUMAN (479-880): 2.35e-88: 298: 29.82		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		481524 HS104_YEAST (1-908): 0: 896: 100.00		HSP73_YEAST (1-642): 5.48e-72: 247: 28.33
+	Hs
		536630 LONM_HUMAN (326-881): 4.43e-84: 292: 13.84		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		526136 HS104_YEAST (1-908): 0: 896: 100.00		HSP72_YEAST (1-382): 1.16e-71: 246: 36.82
+	Sc
		523308 HS104_YEAST (1-908): 0: 896: 100.00		HSP71_YEAST (1-382): 7.04e-71: 244: 36.55
+	Hs
		931100 CLPB_HUMAN (479-880): 2.35e-88: 298: 29.82		HSP72_HUMAN (2-644): 0: 841: 27.08
+	Sc
		481567 HSP78_YEAST (103-867): 0: 744: 42.53		HSP73_YEAST (1-642): 5.48e-72: 247: 28.33
+	Sc
		526301 HSP78_YEAST (103-867): 0: 744: 42.53		HSP72_YEAST (1-382): 1.16e-71: 246: 36.82
+	Sc
		523502 HSP78_YEAST (103-867): 0: 744: 42.53		HSP71_YEAST (1-382): 7.04e-71: 244: 36.55