HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: LARP1 (Q6PKG0)
La-related protein 1 (La ribonucleoprotein domain family member 1)
Gene: LARP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 29884807, 35271311, 27460707
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains La~RRM_1
Common GO terms GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005737 - cytoplasm
GO:0048255 - mRNA stabilization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 526
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024