HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: CCAR1 (Q8IX12)
Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain)
Gene: CCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29884807, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 1150
+	Hs
		1220133 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		CCAR1_HUMAN (1-1150): 0: 720: 100.00
+	Ce
		104289 Q18265_CAEEL (286-374): 3e-10: 64.5: 39.56		G5EBS4_CAEEL (137-546): 8.56e-126: 397: 36.03
+	Hs
		1230495 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		CCAR2_HUMAN (667-1140): 1.1e-32: 139: 27.11
+	Hs
		726926 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		CCAR2_HUMAN (667-1140): 1.1e-32: 139: 27.11
+	Hs
		967273 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		CCAR2_HUMAN (667-1140): 1.1e-32: 139: 27.11
+	Hs
		725096 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32