HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: GPTC8 (Q9UKJ3)
G patch domain-containing protein 8
Gene: GPATCH8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 1502
+	Hs
		967506 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		GPTC8_HUMAN (1-1502): 0: 787: 100.00
+	Hs
		967233 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		NIPBL_HUMAN (249-1350): 2.11e-111: 393: 13.47
+	Hs
		725096 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		MYH10_HUMAN (93-975): 5.18e-52: 204: 9.51
+	Hs
		1246342 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		THOC2_HUMAN (580-1024): 3.56e-35: 149: 15.03
+	Hs
		726945 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		THOC2_HUMAN (580-1024): 3.56e-35: 149: 15.03
+	Hs
		1246388 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		THOC2_HUMAN (580-1024): 3.56e-35: 149: 15.03
+	Hs
		1271171 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SCAFB_HUMAN (482-1022): 1.33e-16: 88.3: 10.30
+	Hs
		1049692 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		EIF3A_HUMAN (648-1008): 2.86e-09: 64.3: 15.18