HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: RA54B (Q9Y620)
DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B)
Gene: RAD54B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25192599
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 526 Hs			1 910
+	Hs
		847043 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SMCA4_HUMAN (1-884): 0: 617: 19.03
+	Hs
		1018620 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		CHD3_HUMAN (114-856): 0: 608: 22.86
+	Hs
		726671 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		SMCA4_HUMAN (1-884): 0: 617: 19.03
+	Hs
		726779 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		CHD3_HUMAN (114-856): 0: 608: 22.86
+	Hs
		1059773 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		CHD4_HUMAN (115-858): 0: 593: 21.91
+	Hs
		1109067 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		CHD9_HUMAN (18-904): 0: 628: 19.69
+	Hs
		846937 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		SMCA4_HUMAN (1-884): 0: 617: 19.03
+	Hs
		726820 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		CHD4_HUMAN (115-858): 0: 593: 21.91
+	Hs
		967134 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		CHD3_HUMAN (114-856): 0: 608: 22.86
+	Mm
		1142756 EWS_MOUSE (3-451): 2.8e-30: 127: 35.56		SMCA1_MOUSE (171-904): 0: 598: 24.57
+	Hs
		516702 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		CHD8_HUMAN (2-904): 0: 652: 19.90
+	Hs
		967177 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		CHD4_HUMAN (115-858): 0: 593: 21.91
+	Mm
		1142755 EWS_MOUSE (3-451): 2.8e-30: 127: 35.56		CHD4_MOUSE (115-858): 0: 593: 21.78
+	Hs
		212133 HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30		CHD3_HUMAN (114-856): 0: 608: 22.86
+	Hs
		212140 HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30		CHD4_HUMAN (115-858): 0: 593: 21.91
+	Hs
		1018458 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		CHD3_HUMAN (114-856): 0: 608: 22.86
+	Hs
		516483 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		CHD3_HUMAN (114-856): 0: 608: 22.86
+	Hs
		1031332 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		CHD4_HUMAN (115-858): 0: 593: 21.91
+	Hs
		516522 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		CHD4_HUMAN (115-858): 0: 593: 21.91
+	Hs
		212131 HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30		ERCC6_HUMAN (291-815): 1.21e-76: 275: 34.33