HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 673
+	Mm
		1142920 ITSN1_MOUSE (385-1370): 9.29e-67: 253: 16.02		FXR1_MOUSE (14-673): 0: 981: 62.83
+	Mm
		1142913 NCOR2_MOUSE (306-2078): 1.92e-52: 206: 9.57		FXR1_MOUSE (14-673): 0: 981: 62.83
+	Hs
		844303 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		FXR2_HUMAN (1-673): 0: 1004: 100.00
+	Hs
		843980 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		FXR1_HUMAN (14-673): 0: 798: 51.34
+	Hs
		311796 TACC2_HUMAN (292-1170): 8.5e-09: 63.3: 8.69		FXR1_HUMAN (14-673): 0: 798: 51.34
+	Mm
		1207112 NCOR2_MOUSE (306-2078): 1.92e-52: 206: 9.57		Q8BPK8_MOUSE (14-344): 0: 621: 71.90
+	Mm
		1207088 BCL9_MOUSE (430-1615): 1.68e-15: 85.2: 8.98		Q8BPK8_MOUSE (14-344): 0: 621: 71.90
+	Mm
		729608 NCOR2_MOUSE (306-2078): 1.92e-52: 206: 9.57		FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20
+	Hs
		577622 SON_HUMAN (277-1824): 2.67e-46: 186: 9.42		FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42
+	Hs
		989216 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42
+	Mm
		729586 BCL9_MOUSE (430-1615): 1.68e-15: 85.2: 8.98		FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20
+	Hs
		311804 TACC2_HUMAN (292-1170): 8.5e-09: 63.3: 8.69		FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42