HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: PKHG6 (Q3KR16)
Pleckstrin homology domain-containing family G member 6 (PH domain-containing family G member 6) (Myosin-interacting guanine nucleotide exchange factor) (MyoGEF)
Gene: PLEKHG6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32203420, unassigned2213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 790
+	Hs
		727262 NU214_HUMAN (1-2090): 0: 691: 100.00		ITSN1_HUMAN (60-568): 5.98e-78: 277: 18.72
+	Hs
		1078919 ITSN1_HUMAN (385-1370): 7.95e-65: 247: 14.42		ITSN2_HUMAN (2-574): 7.24e-82: 288: 15.70
+	Hs
		1078828 ITSN1_HUMAN (385-1370): 7.95e-65: 247: 14.42		ITSN1_HUMAN (60-568): 5.98e-78: 277: 18.72
+	Hs
		1078907 PTN23_HUMAN (547-1430): 4.5e-47: 189: 13.98		ITSN1_HUMAN (60-568): 5.98e-78: 277: 18.72
+	Hs
		577694 SON_HUMAN (277-1824): 2.67e-46: 186: 9.42		ECT2_HUMAN (77-645): 3.51e-80: 277: 19.26
+	Hs
		1056991 MDC1_HUMAN (423-1348): 9.84e-37: 155: 10.01		ECT2_HUMAN (77-645): 3.51e-80: 277: 19.26
+	Hs
		855816 TITIN_HUMAN (276-1124): 1.14e-10: 69.5: 8.16		VAV2_HUMAN (81-644): 5.43e-90: 304: 17.50
+	Hs
		858054 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		ECT2_HUMAN (77-645): 3.51e-80: 277: 19.26