HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 400
+	Hs
		727287 NU214_HUMAN (1-2090): 0: 691: 100.00		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		577698 SON_HUMAN (277-1824): 2.67e-46: 186: 9.42		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1056998 MDC1_HUMAN (423-1348): 9.84e-37: 155: 10.01		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1344557 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1302925 MINT_HUMAN (283-1766): 1.23e-24: 115: 7.56		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		858057 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Mm
		1265847 NCOR2_MOUSE (306-2078): 1.92e-52: 206: 9.57		SIR1_MOUSE (78-380): 5.54e-78: 256: 19.94
+	Hs
		1056888 MDC1_HUMAN (423-1348): 9.84e-37: 155: 10.01		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		858011 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1170068 SRCAP_HUMAN (312-1939): 4.05e-09: 64.4: 9.42		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87