HitPredict

Interactor 1: HNF1B (P35680)
Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2) (Variant hepatic nuclear factor 1) (vHNF1)
Gene: HNF1B

Interactor 2: MCAF1 (Q6VMQ6)
Activating transcription factor 7-interacting protein 1 (ATF-interacting protein) (ATF-IP) (ATF7-interacting protein) (ATFa-associated modulator) (hAM) (MBD1-containing chromatin-associated factor 1) (P621)
Gene: ATF7IP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 1270
+	Hs
		595935 HNF1A_HUMAN (1-551): 2.16e-85: 279: 53.21		MCAF1_HUMAN (1-1270): 3.52e-174: 552: 100.00
+	Hs
		727603 HNF1B_HUMAN (1-557): 6.73e-147: 436: 100.00		CHD7_HUMAN (650-1177): 7.42e-32: 138: 12.63
+	Hs
		727560 HNF1B_HUMAN (1-557): 6.73e-147: 436: 100.00		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		152601 HNF1B_HUMAN (1-557): 6.73e-147: 436: 100.00		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		595941 HNF1A_HUMAN (1-551): 2.16e-85: 279: 53.21		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		152587 HNF1A_HUMAN (1-551): 2.16e-85: 279: 53.21		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		620215 PAX7_HUMAN (84-479): 2.24e-58: 204: 15.58		CHD7_HUMAN (650-1177): 7.42e-32: 138: 12.63
+	Hs
		641583 PAX6_HUMAN (83-460): 3.74e-59: 204: 15.54		CHD7_HUMAN (650-1177): 7.42e-32: 138: 12.63
+	Hs
		620175 PAX7_HUMAN (84-479): 2.24e-58: 204: 15.58		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		641482 PAX6_HUMAN (83-460): 3.74e-59: 204: 15.54		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		988814 PAX8_HUMAN (83-439): 4.26e-37: 144: 9.43		CHD7_HUMAN (650-1177): 7.42e-32: 138: 12.63
+	Hs
		1056866 HMBX1_HUMAN (4-361): 1.12e-61: 210: 21.27		MDC1_HUMAN (663-1169): 2.42e-11: 70.8: 17.22
+	Hs
		641457 PAX6_HUMAN (83-460): 3.74e-59: 204: 15.54		SRCAP_HUMAN (666-1147): 1.03e-10: 68.9: 16.17
+	Hs
		152588 PAX7_HUMAN (84-479): 2.24e-58: 204: 15.58		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		152592 PAX6_HUMAN (83-460): 3.74e-59: 204: 15.54		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		988783 PAX8_HUMAN (83-439): 4.26e-37: 144: 9.43		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		203210 PAX6_HUMAN (83-460): 3.74e-59: 204: 15.54		SYNJ1_HUMAN (900-1257): 4.33e-09: 63.4: 10.73
+	Hs
		973865 PAX2_HUMAN (83-401): 6.33e-36: 141: 9.47		KMT2C_HUMAN (33-1231): 1.44e-27: 124: 9.99
+	Hs
		152634 PAX8_HUMAN (83-439): 4.26e-37: 144: 9.43		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89
+	Hs
		152629 PAX2_HUMAN (83-401): 6.33e-36: 141: 9.47		KMT2D_HUMAN (774-1162): 2.66e-09: 64.2: 14.89