HitPredict

Interactor 1: SOX5 (P35711)
Transcription factor SOX-5
Gene: SOX5

Interactor 2: RCOR3 (Q9P2K3)
REST corepressor 3
Gene: RCOR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 763 Hs			1 495
+	Hs
		727824 SOX5_HUMAN (1-763): 0: 611: 100.00		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		727796 SOX5_HUMAN (1-763): 0: 611: 100.00		MTA3_HUMAN (1-418): 1.98e-89: 287: 15.86
+	Hs
		727935 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		RCOR3_HUMAN (1-495): 1.17e-141: 418: 100.00
+	Hs
		261421 SOX5_HUMAN (1-763): 0: 611: 100.00		NCOR1_HUMAN (35-484): 1.63e-51: 191: 17.04
+	Hs
		727832 SOX5_HUMAN (1-763): 0: 611: 100.00		NCOR2_HUMAN (35-478): 1.59e-48: 182: 18.57
+	Hs
		727940 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		727915 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		MTA3_HUMAN (1-418): 1.98e-89: 287: 15.86
+	Hs
		727860 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		MTA1_HUMAN (1-433): 2.17e-85: 279: 15.62
+	Hs
		261422 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		NCOR1_HUMAN (35-484): 1.63e-51: 191: 17.04
+	Hs
		727951 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		NCOR2_HUMAN (35-478): 1.59e-48: 182: 18.57
+	Hs
		1300986 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		883318 SOX8_HUMAN (551-633): 8.17e-37: 146: 48.19		RCOR1_HUMAN (1-384): 4.93e-99: 308: 62.69
+	Hs
		296107 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		MTA2_HUMAN (1-478): 7.19e-92: 295: 15.71
+	Hs
		295961 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MTA2_HUMAN (1-478): 7.19e-92: 295: 15.71
+	Hs
		1300922 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		MTA3_HUMAN (1-418): 1.98e-89: 287: 15.86
+	Hs
		1031932 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		MTA1_HUMAN (1-433): 2.17e-85: 279: 15.62
+	Hs
		818012 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MTA1_HUMAN (1-433): 2.17e-85: 279: 15.62
+	Hs
		261435 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		NCOR1_HUMAN (35-484): 1.63e-51: 191: 17.04
+	Hs
		818368 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		TREF1_HUMAN (1-314): 6.01e-45: 171: 20.48
+	Hs
		818240 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MIER1_HUMAN (1-307): 1.08e-41: 157: 18.68