HitPredict

Interactor 1: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	12620224, 17049045, 34056863, 37968396, 14690608, 21179020
Identification Methods	pull down, affinity chromatography technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 686 Sc			1 136
+	Sp
		457186 YK82_SCHPO (6-672): 2.66e-107: 343: 24.89		H31_SCHPO (1-136): 1.17e-59: 182: 92.65
+	Dm
		356102 Q9VC96_DROME (114-684): 3.93e-68: 245: 16.47		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Hs
		952418 BRWD3_HUMAN (103-567): 1.39e-64: 235: 14.96		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Dm
		356083 Q4V5A7_DROME (123-684): 1.91e-64: 227: 13.88		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Hs
		600123 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		600126 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		600156 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		935266 BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952643 BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1086327 BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		1174668 BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Hs
		935249 BRD9_HUMAN (14-547): 6.79e-57: 205: 11.35		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952631 BRD9_HUMAN (14-547): 6.79e-57: 205: 11.35		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Sc
		902004 RSC4_YEAST (105-686): 4.92e-54: 198: 15.22		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		600099 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		828386 BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73
+	Hs
		934930 PB1_HUMAN (91-664): 4.19e-38: 154: 11.97		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952441 PB1_HUMAN (91-664): 4.19e-38: 154: 11.97		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Sc
		730892 RSC4_YEAST (105-686): 4.92e-54: 198: 15.22		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	Hs
		828285 PB1_HUMAN (91-664): 4.19e-38: 154: 11.97		CENPA_HUMAN (9-133): 2.55e-40: 133: 47.73