HitPredict

Interactor 1: PTN12 (P35831)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (MPTP-PEST) (Protein-tyrosine phosphatase P19) (P19-PTP)
Gene: Ptpn12

Interactor 2: SHC1 (P98083)
SHC-transforming protein 1 (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 12052829, 20697350, 20075861
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, nuclear magnetic resonance, isothermal titration calorimetry
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~Y_phosphatase
Common GO terms GO:0005829 - cytosol
GO:0005925 - focal adhesion
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 775
Mm

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024