HitPredict

Interactor 1: PARP (P35875)
Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase) (ADPRT) (Poly[ADP-ribose] synthase) (Protein ADP-ribosyltransferase Parp) (EC 2.4.2.-)
Gene: PARP

Interactor 2: H4 (P84040)
Histone H4
Gene: His4

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	31028139, 17827147, 24508391
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005694 - chromosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 994 Dm			1 103
+	Hs
		918087 PARP2_HUMAN (439-992): 0: 627: 36.51		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		836702 DNLI3_HUMAN (4-107): 1.92e-28: 125: 21.05		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917500 ZCCHV_HUMAN (632-988): 9.55e-26: 116: 13.86		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		455300 PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		917382 PAR10_HUMAN (783-987): 6.43e-19: 94.6: 15.35		H4_HUMAN (1-103): 1.72e-48: 151: 99.03