HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: DX39B (Q13838)
Spliceosome RNA helicase DDX39B (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein UAP56) (HLA-B-associated transcript 1 protein)
Gene: DDX39B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35973989
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 428
+	Hs
		444537 K2C7_HUMAN (86-542): 4.82e-131: 395: 52.62		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		380609 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		133832 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		DDX3X_HUMAN (3-423): 4.76e-124: 375: 27.84
+	Hs
		1046178 KRT84_HUMAN (5-589): 2.17e-100: 320: 44.20		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		213944 KRT86_HUMAN (72-557): 8.74e-87: 281: 44.35		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		531566 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		380473 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		821655 K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		1046088 K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		359489 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		DX39B_HUMAN (1-428): 6.01e-135: 395: 100.00
+	Hs
		133866 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		DDX3X_HUMAN (3-423): 4.76e-124: 375: 27.84
+	Hs
		133831 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		DDX3X_HUMAN (3-423): 4.76e-124: 375: 27.84
+	Hs
		134103 K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95		DDX3X_HUMAN (3-423): 4.76e-124: 375: 27.84
+	Hs
		133822 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		DDX3X_HUMAN (3-423): 4.76e-124: 375: 27.84
+	Hs
		133904 K22E_HUMAN (1-517): 4.22e-68: 235: 100.00		DDX3X_HUMAN (3-423): 4.76e-124: 375: 27.84
+	Hs
		380574 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		IF4A3_HUMAN (52-415): 7.9e-81: 256: 38.36
+	Hs
		318784 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		IF4A3_HUMAN (52-415): 7.9e-81: 256: 38.36
+	Hs
		531537 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		IF4A3_HUMAN (52-415): 7.9e-81: 256: 38.36
+	Hs
		380447 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		IF4A3_HUMAN (52-415): 7.9e-81: 256: 38.36
+	Hs
		757638 K2C71_HUMAN (1-570): 6.15e-82: 269: 51.23		IF4A3_HUMAN (52-415): 7.9e-81: 256: 38.36