HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 81
+	Hs
		380621 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		318811 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		531578 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00
+	Hs
		965429 K22O_HUMAN (1-506): 1.14e-73: 250: 63.95		NEDD8_HUMAN (1-81): 2.07e-30: 103: 100.00