HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: ZUP1 (Q96AP4)
Zinc finger-containing ubiquitin peptidase 1 (EC 3.4.19.12) (Lys-63-specific deubiquitinase ZUFSP) (DUB) (Zinc finger with UFM1-specific peptidase domain protein)
Gene: ZUP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29563501
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 578
+	Hs
		380664 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		ZUP1_HUMAN (1-578): 0: 794: 100.00
+	Hs
		531615 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		ZUP1_HUMAN (1-578): 0: 794: 100.00
+	Hs
		380509 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		ZUP1_HUMAN (1-578): 0: 794: 100.00
+	Hs
		1192455 K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95		ZUP1_HUMAN (1-578): 0: 794: 100.00
+	Hs
		359523 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		ZUP1_HUMAN (1-578): 0: 794: 100.00
+	Hs
		517776 K2C3_HUMAN (27-494): 2.18e-66: 230: 64.32		ZUP1_HUMAN (1-578): 0: 794: 100.00
+	Hs
		409101 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		ZN484_HUMAN (4-218): 3.05e-11: 68.4: 16.82