HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: RN208 (Q9H0X6)
RING finger protein 208
Gene: RNF208

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31862882
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 261
+	Hs
		409229 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		444555 K2C7_HUMAN (86-542): 4.82e-131: 395: 52.62		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		380688 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1205252 K2C73_HUMAN (1-598): 8.9e-92: 296: 51.00		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		318884 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		531631 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		380520 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1110345 K2C71_HUMAN (1-570): 6.15e-82: 269: 51.23		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		821688 K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1192466 K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		359536 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1062066 K2C72_HUMAN (87-494): 7.09e-77: 255: 61.28		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		1186167 K2C74_HUMAN (1-563): 1.33e-76: 255: 51.69		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		965459 K22O_HUMAN (1-506): 1.14e-73: 250: 63.95		RN208_HUMAN (1-261): 3.04e-117: 337: 100.00
+	Hs
		380572 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76
+	Hs
		318781 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76
+	Hs
		318903 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		TRIM1_HUMAN (122-231): 1.51e-22: 98.3: 22.22
+	Hs
		359468 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76
+	Hs
		734597 K22O_HUMAN (1-506): 1.14e-73: 250: 63.95		TRI23_HUMAN (116-259): 1.31e-26: 109: 22.76
+	Hs
		965463 K22O_HUMAN (1-506): 1.14e-73: 250: 63.95		TRIM1_HUMAN (122-231): 1.51e-22: 98.3: 22.22