Interactor 1: VGFR3 (P35917)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: Flt4
Interactor 2: VGFR2 (P35918)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase NYK) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: Kdr
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.58 | 1.00 | 0.767 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | I-set~I-set, Ig_3~I-set, Ig_3~Ig_3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, VEGFR-2_TMD~VEGFR-2_TMD |
Common GO terms | GO:0001525 - angiogenesis GO:0001934 - positive regulation of protein phosphorylation GO:0001938 - positive regulation of endothelial cell proliferation GO:0001945 - lymph vessel development GO:0005021 - vascular endothelial growth factor receptor activity and 13 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024