HitPredict

Interactor 1: FMR1 (P35922)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) (mFmr1p)
Gene: FMR1

Interactor 2: PRC2A (Q7TSC1)
Protein PRRC2A (HLA-B-associated transcript 2) (Proline-rich and coiled-coil-containing protein 2A)
Gene: Prrc2a

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28671696
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 614 Mm			1 2158
+	Hs
		820894 FMR1_HUMAN (1-614): 0: 995: 93.99		PRC2A_HUMAN (1-2158): 2.68e-173: 587: 86.33
+	Hs
		988930 FMR1_HUMAN (1-614): 0: 995: 93.99		PRC2B_HUMAN (1-2141): 2.62e-77: 288: 23.47
+	Mm
		1142853 FXR1_MOUSE (1-334): 0: 589: 73.65		PRC2A_MOUSE (1-2158): 0: 646: 100.00
+	Hs
		820851 FXR1_HUMAN (1-334): 0: 596: 73.95		PRC2A_HUMAN (1-2158): 2.68e-173: 587: 86.33
+	Mm
		729462 FMR1_MOUSE (1-614): 0: 1011: 100.00		PRC2C_MOUSE (272-2157): 2.63e-20: 101: 9.36
+	Mm
		729608 FMR1_MOUSE (1-614): 0: 1011: 100.00		NCOR2_MOUSE (896-2157): 8.74e-13: 76.5: 9.21
+	Mm
		729531 FMR1_MOUSE (1-614): 0: 1011: 100.00		PRC2B_MOUSE (561-2020): 3.63e-10: 67.6: 9.93
+	Hs
		311804 FMR1_HUMAN (1-614): 0: 995: 93.99		TACC2_HUMAN (29-1370): 5.46e-14: 80.7: 9.76
+	Hs
		989216 FMR1_HUMAN (1-614): 0: 995: 93.99		PRC2C_HUMAN (294-2152): 2.19e-10: 68.8: 9.46
+	Hs
		843719 FXR1_HUMAN (1-334): 0: 596: 73.95		PRC2B_HUMAN (1-2141): 2.62e-77: 288: 23.47
+	Hs
		820852 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		PRC2A_HUMAN (1-2158): 2.68e-173: 587: 86.33
+	Hs
		843899 FXR1_HUMAN (1-334): 0: 596: 73.95		TARA_HUMAN (631-2037): 8.31e-25: 116: 11.20
+	Mm
		1111986 FXR1_MOUSE (1-334): 0: 589: 73.65		PRC2C_MOUSE (272-2157): 2.63e-20: 101: 9.36
+	Hs
		311796 FXR1_HUMAN (1-334): 0: 596: 73.95		TACC2_HUMAN (29-1370): 5.46e-14: 80.7: 9.76
+	Mm
		1142913 FXR1_MOUSE (1-334): 0: 589: 73.65		NCOR2_MOUSE (896-2157): 8.74e-13: 76.5: 9.21
+	Hs
		843980 FXR1_HUMAN (1-334): 0: 596: 73.95		PRC2C_HUMAN (294-2152): 2.19e-10: 68.8: 9.46
+	Mm
		1142852 FXR1_MOUSE (1-334): 0: 589: 73.65		PRC2B_MOUSE (561-2020): 3.63e-10: 67.6: 9.93
+	Hs
		844097 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		PRC2B_HUMAN (1-2141): 2.62e-77: 288: 23.47
+	Hs
		844237 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		TARA_HUMAN (631-2037): 8.31e-25: 116: 11.20
+	Hs
		844303 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		PRC2C_HUMAN (294-2152): 2.19e-10: 68.8: 9.46