Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 20190562, 16007196, 10102632, 28303365, 17293873, 20080685, 20660291
Identification Methods enzymatic study, biochemical, transmission electron microscopy, x-ray crystallography, cosedimentation in solution, surface plasmon resonance
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~I-set, ig~I-set, I-set~Ig_2, ig~ig, Ig_2~ig, Ig_2~Ig_2, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, VEGFR-2_TMD~VEGFR-2_TMD
Common GO terms GO:0001525 - angiogenesis
GO:0001541 - ovarian follicle development
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis
GO:0001934 - positive regulation of protein phosphorylation
and 80 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1356
Hs

1 1356
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Last updated: 15 Jul 2024