Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR
Interactor 2: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.91 | 1.00 | 0.958 |
The method score is based on:
Property | Details |
---|---|
Experiments | 20190562, 16007196, 10102632, 28303365, 17293873, 20080685, 20660291 |
Identification Methods | enzymatic study, biochemical, transmission electron microscopy, x-ray crystallography, cosedimentation in solution, surface plasmon resonance |
Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | I-set~I-set, ig~I-set, I-set~Ig_2, ig~ig, Ig_2~ig, Ig_2~Ig_2, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, VEGFR-2_TMD~VEGFR-2_TMD |
Common GO terms | GO:0001525 - angiogenesis GO:0001541 - ovarian follicle development GO:0001569 - branching involved in blood vessel morphogenesis GO:0001570 - vasculogenesis GO:0001934 - positive regulation of protein phosphorylation and 80 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024