Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 15217908, 19050761
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CH~PK_Tyr_Ser-Thr
Common GO terms GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0016477 - cell migration
GO:0043410 - positive regulation of MAPK cascade
GO:0045296 - cadherin binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1356
Hs

1 1657
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Last updated: 15 Jul 2024