HitPredict

Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16049137
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005768 - endosome GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1356 Hs			1 870
+	Hs
		557069 PGFRA_HUMAN (11-545): 1.02e-53: 207: 19.71		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		601480 FGFR2_HUMAN (1-231): 3.47e-24: 112: 9.57		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		572603 VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		609215 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		507913 FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		607921 FGFR4_HUMAN (538-817): 2.68e-15: 83.5: 14.42		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		601616 FGFR2_HUMAN (1-231): 3.47e-24: 112: 9.57		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		609615 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		508270 FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		608198 FGFR4_HUMAN (538-817): 2.68e-15: 83.5: 14.42		DYN3_HUMAN (1-870): 0: 994: 78.41