HitPredict

Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37226882
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1356 Hs			1 147
+	Hs
		729629 VGFR2_HUMAN (1-1356): 0: 1028: 100.00		UB2D1_HUMAN (1-147): 7.06e-83: 241: 89.12
+	Hs
		729631 VGFR2_HUMAN (1-1356): 0: 1028: 100.00		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22
+	Hs
		572611 VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22
+	Hs
		609211 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		UBE2A_HUMAN (2-144): 1.41e-70: 210: 39.16
+	Hs
		609235 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22
+	Hs
		729254 VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93		UBE2N_HUMAN (4-147): 7.67e-69: 206: 47.22