HitPredict

Interactor 1: LHS1 (P36016)
Heat shock protein 70 homolog LHS1 (EC 3.6.1.-)
Gene: LHS1

Interactor 2: IPI3 (P53877)
Pre-rRNA-processing protein IPI3 (Involved in processing IST2 protein 3)
Gene: IPI3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.526

Property	Details
Experiments	22875988, 19536198
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 881 Sc			1 555
+	Sc
		731129 LHS1_YEAST (1-881): 0: 993: 100.00		COPA_YEAST (5-320): 4.48e-27: 118: 10.62
+	Hs
		714020 HS71L_HUMAN (18-688): 0: 821: 19.73		POC1A_HUMAN (1-331): 4.77e-58: 200: 7.78
+	Hs
		564125 HSP76_HUMAN (22-699): 0: 805: 20.41		POC1A_HUMAN (1-331): 4.77e-58: 200: 7.78
+	Hs
		504412 HSP7C_HUMAN (18-682): 0: 802: 19.61		POC1A_HUMAN (1-331): 4.77e-58: 200: 7.78
+	Hs
		503817 HSP7C_HUMAN (18-682): 0: 802: 19.61		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Hs
		504344 HSP7C_HUMAN (18-682): 0: 802: 19.61		WDR5B_HUMAN (380-541): 1.93e-25: 109: 11.11
+	Hs
		503743 HSP7C_HUMAN (18-682): 0: 802: 19.61		COPA_HUMAN (6-360): 1.8e-19: 94.9: 10.31
+	Hs
		503614 HSP7C_HUMAN (18-682): 0: 802: 19.61		LIS1_HUMAN (437-521): 1.16e-17: 87.3: 14.12
+	Hs
		504679 HSP7C_HUMAN (18-682): 0: 802: 19.61		WDR18_HUMAN (245-486): 2.51e-15: 80.2: 11.28
+	Sc
		492044 HSP71_YEAST (76-574): 4.96e-31: 132: 24.55		IPI3_YEAST (1-555): 1.87e-94: 300: 95.16
+	Hs
		903642 HYOU1_HUMAN (21-481): 2.67e-52: 200: 29.83		WDR5_HUMAN (2-287): 3.87e-43: 158: 13.06
+	Sc
		605373 HSP74_YEAST (76-668): 1.86e-31: 133: 23.32		COPA_YEAST (5-320): 4.48e-27: 118: 10.62
+	Sc
		491987 HSP71_YEAST (76-574): 4.96e-31: 132: 24.55		COPA_YEAST (5-320): 4.48e-27: 118: 10.62
+	Sc
		450129 HSP73_YEAST (76-668): 9.25e-31: 131: 23.71		COPA_YEAST (5-320): 4.48e-27: 118: 10.62
+	Sc
		494582 HSP72_YEAST (76-574): 1.07e-30: 130: 24.45		COPA_YEAST (5-320): 4.48e-27: 118: 10.62
+	Sc
		490983 HSP71_YEAST (76-574): 4.96e-31: 132: 24.55		TAF5_YEAST (141-424): 3.83e-18: 90.1: 11.86
+	Sc
		450018 HSP73_YEAST (76-668): 9.25e-31: 131: 23.71		TAF5_YEAST (141-424): 3.83e-18: 90.1: 11.86
+	Sc
		493759 HSP72_YEAST (76-574): 1.07e-30: 130: 24.45		TAF5_YEAST (141-424): 3.83e-18: 90.1: 11.86
+	Sc
		490481 HSP71_YEAST (76-574): 4.96e-31: 132: 24.55		PWP2_YEAST (3-320): 5.66e-09: 61.1: 9.66
+	Sc
		493321 HSP72_YEAST (76-574): 1.07e-30: 130: 24.45		PWP2_YEAST (3-320): 5.66e-09: 61.1: 9.66