HitPredict

Interactor 1: SN114 (P36048)
Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)
Gene: SNU114

Interactor 2: LSM4 (P40070)
U6 snRNA-associated Sm-like protein LSm4 (Like-SM protein 4)
Gene: LSM4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GTP_EFTU~LSM
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005737 - cytoplasm and 1 others more... GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1008 Sc			1 187
+	Hs
		1064898 U5S1_HUMAN (2-1007): 0: 898: 31.43		LSM4_HUMAN (1-98): 5.13e-45: 147: 38.78
+	Dm
		218367 Q9VAX8_DROME (2-1007): 0: 914: 31.92		SMD3_DROME (2-106): 2.68e-34: 120: 21.70
+	Hs
		912641 U5S1_HUMAN (2-1007): 0: 898: 31.43		SMD3_HUMAN (2-108): 1.35e-33: 117: 26.17
+	Sc
		731734 SN114_YEAST (1-1008): 0: 895: 100.00		SMD3_YEAST (2-104): 1.92e-30: 108: 26.21
+	Dm
		218354 EF2_DROME (117-995): 0: 842: 24.65		SMD3_DROME (2-106): 2.68e-34: 120: 21.70
+	Sp
		292972 SN114_SCHPO (1-1007): 0: 841: 32.82		SMD3_SCHPO (2-108): 7.97e-34: 117: 20.18