HitPredict

Interactor 1: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2

Interactor 2: ACTH (P63267)
Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]
Gene: ACTG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17620599
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0010628 - positive regulation of gene expression
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 409 Hs			1 376
+	Hs
		732615 ARRB2_HUMAN (1-409): 0: 688: 100.00		ACTBL_HUMAN (1-376): 0: 713: 87.77
+	Hs
		882506 ARRB1_HUMAN (1-407): 0: 661: 76.15		ACTBL_HUMAN (1-376): 0: 713: 87.77
+	Hs
		732501 ARRB2_HUMAN (1-409): 0: 688: 100.00		ACTB_HUMAN (1-376): 0: 601: 93.35
+	Hs
		732532 ARRB2_HUMAN (1-409): 0: 688: 100.00		ACTC_HUMAN (2-376): 0: 598: 98.67
+	Hs
		882425 ARRB1_HUMAN (1-407): 0: 661: 76.15		ACTB_HUMAN (1-376): 0: 601: 93.35
+	Hs
		882447 ARRB1_HUMAN (1-407): 0: 661: 76.15		ACTS_HUMAN (2-376): 0: 598: 98.13