HitPredict

Interactor 1: VPS24 (P36095)
Vacuolar protein-sorting-associated protein 24 (DOA4-independent degradation protein 3) (ESCRT-III complex subunit VPS24)
Gene: VPS24

Interactor 2: SNF7 (P39929)
Vacuolar-sorting protein SNF7 (DOA4-independent degradation protein 1) (Sucrose nonfermenting protein 7) (Vacuolar protein-sorting-associated protein 32)
Gene: SNF7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 24058170, 31246173, 31273031, 35445263, 19725809, 18854142, 15086794, 16554755, 18467557, 37968396, 20702581
Identification Methods pull down, affinity chromatography technology, two hybrid, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Snf7~Snf7
Common GO terms GO:0000815 - ESCRT III complex
GO:0005737 - cytoplasm
GO:0005771 - multivesicular body
GO:0015031 - protein transport
GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 224
Sc

1 240
+ Sc
+ Ce
+ At
+ Sc
+ Sc
+ At
+ Dm
+ Dm
+ Hs
+ Hs
+ At
+ Sc
+ Sc
+ At
+ At
+ Hs
+ Dm
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024