HitPredict

Interactor 1: VPS24 (P36095)
Vacuolar protein-sorting-associated protein 24 (DOA4-independent degradation protein 3) (ESCRT-III complex subunit VPS24)
Gene: VPS24

Interactor 2: VPS4 (P52917)
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)
Gene: VPS4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24711499, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0015031 - protein transport GO:0045324 - late endosome to vacuole transport GO:0070676 - intralumenal vesicle formation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 224 Sc			1 437
+	Sc
		732854 DID4_YEAST (12-223): 5.58e-51: 166: 23.50		VPS4_YEAST (1-437): 9.44e-127: 375: 100.00
+	At
		1352475 VPS2A_ARATH (9-223): 1.14e-53: 173: 22.12		VPS4_ARATH (4-436): 3.27e-116: 348: 53.46
+	Hs
		208804 CHM2A_HUMAN (10-223): 8.3e-46: 153: 20.56		VPS4B_HUMAN (2-436): 2.84e-118: 354: 60.50
+	Mm
		804060 CHM2A_MOUSE (10-223): 6.6e-47: 156: 20.56		VPS4B_MOUSE (2-436): 2.92e-117: 351: 60.72
+	Hs
		1357379 CHMP3_HUMAN (11-224): 5.68e-47: 156: 28.97		VPS4A_HUMAN (3-435): 7.08e-117: 350: 58.73
+	Hs
		208869 CHM2A_HUMAN (10-223): 8.3e-46: 153: 20.56		VPS4A_HUMAN (3-435): 7.08e-117: 350: 58.73
+	Hs
		260164 CHM2B_HUMAN (6-215): 2.62e-44: 149: 20.48		VPS4B_HUMAN (2-436): 2.84e-118: 354: 60.50
+	At
		1013169 VPS2B_ARATH (9-223): 1.79e-45: 152: 18.06		VPS4_ARATH (4-436): 3.27e-116: 348: 53.46
+	Dm
		1371193 Q9VN02_DROME (11-224): 2.57e-47: 157: 30.23		Q9Y162_DROME (1-436): 3.05e-114: 343: 57.43
+	Hs
		1357378 CHM2B_HUMAN (6-215): 2.62e-44: 149: 20.48		VPS4A_HUMAN (3-435): 7.08e-117: 350: 58.73
+	Dm
		1373132 Q9VRJ5_DROME (9-211): 3.44e-45: 151: 23.65		Q9Y162_DROME (1-436): 3.05e-114: 343: 57.43
+	Dm
		1362012 Q9VBI3_DROME (9-204): 7.19e-42: 144: 18.37		Q9Y162_DROME (1-436): 3.05e-114: 343: 57.43
+	At
		1352776 CHM1B_ARATH (23-218): 4.76e-37: 130: 15.31		VPS4_ARATH (4-436): 3.27e-116: 348: 53.46
+	Hs
		260156 CHM1A_HUMAN (23-216): 1.31e-34: 123: 18.56		VPS4B_HUMAN (2-436): 2.84e-118: 354: 60.50
+	Dm
		1248702 Q8SXB1_DROME (16-204): 1.71e-37: 132: 17.99		Q9Y162_DROME (1-436): 3.05e-114: 343: 57.43
+	Hs
		1336687 CHM1A_HUMAN (23-216): 1.31e-34: 123: 18.56		VPS4A_HUMAN (3-435): 7.08e-117: 350: 58.73
+	Hs
		260145 CHM1B_HUMAN (24-219): 1.15e-32: 118: 14.80		VPS4B_HUMAN (2-436): 2.84e-118: 354: 60.50
+	Dm
		1279493 Q95SH2_DROME (24-214): 1.34e-35: 126: 13.09		Q9Y162_DROME (1-436): 3.05e-114: 343: 57.43
+	Hs
		208865 CHM2A_HUMAN (10-223): 8.3e-46: 153: 20.56		SPAST_HUMAN (112-367): 1.5e-66: 225: 46.62
+	Hs
		1185555 CHM1B_HUMAN (24-219): 1.15e-32: 118: 14.80		SPAST_HUMAN (112-367): 1.5e-66: 225: 46.62