Interactor 1: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2
Interactor 2: CLH1 (Q00610)
Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17)
Gene: CLTC
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.78 | 1.00 | 0.885 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32962859, 9169477, 35044719, unassigned3413 |
| Identification Methods | affinity chromatography technology, pull down, phage display, fluorescence polarization spectroscopy |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arrestin_C~Clathrin_propel |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031623 - receptor internalization |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
