HitPredict

Interactor 1: VPS24 (P36095)
Vacuolar protein-sorting-associated protein 24 (DOA4-independent degradation protein 3) (ESCRT-III complex subunit VPS24)
Gene: VPS24

Interactor 2: IST1 (P53843)
Vacuolar protein sorting-associated protein IST1 (Increased sodium tolerance protein 1)
Gene: IST1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	31273031, 35445263, 28183979
Identification Methods	affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0015031 - protein transport
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 224 Sc			1 298
+	Sc
		732856 DID4_YEAST (12-223): 5.58e-51: 166: 23.50		IST1_YEAST (1-298): 9.42e-92: 275: 100.00
+	Sc
		865241 DID2_YEAST (23-223): 2.03e-30: 113: 17.41		IST1_YEAST (1-298): 9.42e-92: 275: 100.00
+	Dm
		116112 Q9VN02_DROME (11-224): 2.57e-47: 157: 30.23		M9PHL4_DROME (7-197): 4.03e-59: 195: 29.74
+	Dm
		116116 Q9VRJ5_DROME (9-211): 3.44e-45: 151: 23.65		M9PHL4_DROME (7-197): 4.03e-59: 195: 29.74
+	Dm
		116109 Q9VBI3_DROME (9-204): 7.19e-42: 144: 18.37		M9PHL4_DROME (7-197): 4.03e-59: 195: 29.74
+	Ce
		106471 Q9TXI3_CAEEL (23-224): 1.47e-37: 131: 13.37		G5EDV6_CAEEL (9-195): 8.33e-60: 198: 31.25
+	Hs
		867068 CHM1A_HUMAN (23-216): 1.31e-34: 123: 18.56		IST1_HUMAN (11-204): 5.78e-62: 201: 32.14
+	Dm
		116105 Q95SH2_DROME (24-214): 1.34e-35: 126: 13.09		M9PHL4_DROME (7-197): 4.03e-59: 195: 29.74
+	Hs
		867047 CHM1B_HUMAN (24-219): 1.15e-32: 118: 14.80		IST1_HUMAN (11-204): 5.78e-62: 201: 32.14
+	Dm
		1279489 Q95SH2_DROME (24-214): 1.34e-35: 126: 13.09		Q9VRY6_DROME (7-197): 1.26e-57: 192: 29.74