HitPredict

Interactor 1: VPS24 (P36095)
Vacuolar protein-sorting-associated protein 24 (DOA4-independent degradation protein 3) (ESCRT-III complex subunit VPS24)
Gene: VPS24

Interactor 2: VPS60 (Q03390)
Vacuolar protein-sorting-associated protein 60 (Charged multivesicular body protein 5)
Gene: VPS60

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.857

Property	Details
Experiments	31273031, 35445263, 37968396
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0005737 - cytoplasm GO:0005771 - multivesicular body GO:0015031 - protein transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 224 Sc			1 229
+	Ce
		1090380 Q9U2F6_CAEEL (10-223): 1.1e-50: 166: 18.34		Q18886_CAEEL (2-222): 2.41e-42: 144: 19.46
+	Sc
		732860 DID4_YEAST (12-223): 5.58e-51: 166: 23.50		VPS60_YEAST (1-229): 6.19e-42: 143: 100.00
+	Hs
		1349478 CHMP3_HUMAN (11-224): 5.68e-47: 156: 28.97		CHMP5_HUMAN (1-225): 7.1e-43: 146: 28.44
+	Dm
		1371192 Q9VN02_DROME (11-224): 2.57e-47: 157: 30.23		CHMP5_DROME (1-228): 9.42e-43: 145: 27.19
+	Hs
		208864 CHM2A_HUMAN (10-223): 8.3e-46: 153: 20.56		CHMP5_HUMAN (1-225): 7.1e-43: 146: 28.44
+	At
		1276050 VPS2C_ARATH (9-223): 7.64e-51: 165: 20.00		VP322_ARATH (1-227): 5e-38: 133: 19.30
+	At
		287069 VPS2C_ARATH (9-223): 7.64e-51: 165: 20.00		VP321_ARATH (1-220): 8.32e-36: 127: 16.82
+	Sc
		732540 VPS24_YEAST (1-224): 4.81e-51: 166: 100.00		SNF7_YEAST (4-226): 1.29e-34: 125: 20.98
+	Sc
		732845 DID4_YEAST (12-223): 5.58e-51: 166: 23.50		SNF7_YEAST (4-226): 1.29e-34: 125: 20.98
+	Dm
		1249819 Q9VN02_DROME (11-224): 2.57e-47: 157: 30.23		CHM4_DROME (2-222): 5.59e-38: 133: 17.78
+	Hs
		1316088 CHMP3_HUMAN (11-224): 5.68e-47: 156: 28.97		CHM4A_HUMAN (1-229): 8.6e-38: 133: 18.34
+	Hs
		1330574 CHMP3_HUMAN (11-224): 5.68e-47: 156: 28.97		CHM4B_HUMAN (15-220): 3.6e-38: 133: 19.42
+	Sc
		732549 VPS24_YEAST (1-224): 4.81e-51: 166: 100.00		VPS20_YEAST (6-227): 1.29e-33: 122: 17.12
+	Sc
		732861 DID4_YEAST (12-223): 5.58e-51: 166: 23.50		VPS20_YEAST (6-227): 1.29e-33: 122: 17.12
+	Hs
		208860 CHM2A_HUMAN (10-223): 8.3e-46: 153: 20.56		CHM4B_HUMAN (15-220): 3.6e-38: 133: 19.42
+	At
		1209623 VPS2C_ARATH (9-223): 7.64e-51: 165: 20.00		VP201_ARATH (1-228): 6.9e-32: 117: 19.30
+	At
		1276045 VPS2C_ARATH (9-223): 7.64e-51: 165: 20.00		VP202_ARATH (1-228): 8.39e-31: 114: 20.44
+	At
		287066 VPS2B_ARATH (9-223): 1.79e-45: 152: 18.06		VP321_ARATH (1-220): 8.32e-36: 127: 16.82
+	At
		1013164 VPS2A_ARATH (9-223): 1.14e-53: 173: 22.12		VPS2B_ARATH (8-194): 1.08e-12: 66.8: 13.90
+	At
		1013141 VPS2B_ARATH (9-223): 1.79e-45: 152: 18.06		VPS2B_ARATH (8-194): 1.08e-12: 66.8: 13.90