Interactor 1: ARRB2 (P32121)
Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3)
Gene: ARRB2
Interactor 2: TIGIT (Q495A1)
T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3)
Gene: TIGIT
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.90 | 0.586 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24817116 |
| Identification Methods | anti tag coimmunoprecipitation, unspecified method |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Arrestin_C~V-set, Arrestin_N~V-set |
| Common GO terms | GO:0005102 - signaling receptor binding GO:0005886 - plasma membrane GO:0032695 - negative regulation of interleukin-12 production GO:0045953 - negative regulation of natural killer cell mediated cytotoxicity |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
