HitPredict

Interactor 1: SWD2 (P36104)
COMPASS component SWD2 (Complex proteins associated with SET1 protein SWD2) (Set1C component SWD2)
Gene: SWD2

Interactor 2: SET1 (P38827)
Histone-lysine N-methyltransferase, H3 lysine-4 specific (EC 2.1.1.354) (COMPASS component SET1) (Lysine N-methyltransferase 2) (SET domain-containing protein 1)
Gene: SET1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 11752412, 11742990, 32358498, 18849979, 23453808, 11687631, 16554755, 16429126, 26527276, 16921172, 29444071, 30479350, 30325428, 37968396, 22158900, 18083099, 21179020
Identification Methods coimmunoprecipitation, affinity chromatography technology, biochemical, two hybrid, pull down, x-ray crystallography, tandem affinity purification, molecular sieving
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains N-SET~WD40
Common GO terms GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0031509 - subtelomeric heterochromatin formation
GO:0048188 - Set1C/COMPASS complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 329
Sc

1 1080
+ Sp
+ Hs
+ Dm
+ Hs
+ Hs
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024