HitPredict

Interactor 1: DID4 (P36108)
DOA4-independent degradation protein 4 (ESCRT-III complex subunit VPS2) (Vacuolar protein-sorting-associated protein 2) (Vacuolar protein-targeting protein 14)
Gene: DID4

Interactor 2: SNF7 (P39929)
Vacuolar-sorting protein SNF7 (DOA4-independent degradation protein 1) (Sucrose nonfermenting protein 7) (Vacuolar protein-sorting-associated protein 32)
Gene: SNF7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 31246173, 31273031, 35445263, 12194857, 18467557, 32184262, 37968396
Identification Methods pull down, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Snf7~Snf7
Common GO terms GO:0000815 - ESCRT III complex
GO:0005737 - cytoplasm
GO:0005771 - multivesicular body
GO:0015031 - protein transport
GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 232
Sc

1 240
+ Sc
+ At
+ Ce
+ At
+ Sc
+ At
+ Sc
+ Hs
+ At
+ Hs
+ At
+ At
+ Hs
+ At
+ At
+ Hs
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024