HitPredict

Interactor 1: SET3 (P36124)
SET domain-containing protein 3
Gene: SET3

Interactor 2: SWD1 (P39706)
COMPASS component SWD1 (Complex proteins associated with SET1 protein SWD1) (Set1C component SWD1)
Gene: SWD1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35579426
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SET~WD40
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 751 Sc			1 426
+	Sc
		733255 SET3_YEAST (1-751): 0: 685: 100.00		LST8_YEAST (22-306): 2.55e-19: 89.9: 19.93
+	Mm
		876680 KMT2A_MOUSE (6-480): 1.39e-66: 242: 14.75		RBBP5_MOUSE (1-397): 4.12e-78: 253: 28.15
+	Hs
		975258 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		RBBP5_HUMAN (1-397): 2.09e-78: 254: 28.15
+	Hs
		1070808 KMT2B_HUMAN (26-480): 9.72e-50: 191: 13.06		RBBP5_HUMAN (1-397): 2.09e-78: 254: 28.15
+	Hs
		203735 SUV91_HUMAN (301-507): 1.13e-51: 187: 17.14		DAW1_HUMAN (56-424): 9.4e-74: 238: 13.28
+	Zm
		17586 A0A1D6GXC6_MAIZE (100-237): 7.93e-28: 123: 16.67		A0A1D6JRL3_MAIZE (1-404): 1.42e-93: 294: 28.70
+	Sp
		194056 SET1_SCHPO (311-477): 1.1e-27: 122: 17.96		SWD1_SCHPO (1-405): 5.34e-95: 292: 35.29
+	Hs
		1288292 NSD3_HUMAN (78-556): 5.55e-75: 266: 13.05		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	Hs
		331862 NSD2_HUMAN (122-556): 4.59e-74: 264: 13.29		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	Hs
		975304 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	At
		1319861 ATX1_ARATH (97-496): 7.97e-64: 232: 13.40		WDR5A_ARATH (3-159): 5.05e-26: 109: 11.06
+	Hs
		903149 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74
+	Hs
		1288387 KMT2B_HUMAN (26-480): 9.72e-50: 191: 13.06		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	Hs
		1288291 SETD2_HUMAN (164-702): 1.1e-47: 185: 12.46		SNR40_HUMAN (7-136): 3.56e-30: 121: 16.42
+	Hs
		903604 KMT2B_HUMAN (26-480): 9.72e-50: 191: 13.06		WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74
+	Hs
		975303 KMT2A_HUMAN (25-480): 9.79e-60: 222: 14.56		FBXW7_HUMAN (3-95): 3.57e-11: 67.2: 14.43
+	Hs
		1317584 SETD2_HUMAN (164-702): 1.1e-47: 185: 12.46		NLE1_HUMAN (243-415): 3.68e-22: 100: 10.92
+	Hs
		1281353 DIDO1_HUMAN (16-229): 1.84e-41: 165: 16.74		FBXW7_HUMAN (3-95): 3.57e-11: 67.2: 14.43
+	Hs
		903609 SET1B_HUMAN (210-477): 3.99e-27: 120: 14.44		WDR5_HUMAN (245-419): 2.37e-22: 98.8: 11.74
+	Dm
		1358851 MBDR2_DROME (30-221): 4.75e-35: 145: 21.03		WDS_DROME (300-425): 8.25e-12: 68: 7.14