Interactor 1: SPC34 (P36131)
DASH complex subunit SPC34 (34 kDa spindle pole component protein) (Outer kinetochore protein SPC34)
Gene: SPC34

Interactor 2: DUO1 (P53168)
DASH complex subunit DUO1 (Death upon overproduction protein 1) (Outer kinetochore protein DUO1)
Gene: DUO1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.932

The method score is based on:

Property Details
Experiments 11283351, 10655498, 12925767, 16554755, 17634282, 34313341, 37968396, 32997987, 20730753, 25382489, 11799062, 14627828, 15640796, 18364702, 17460120, 33851957
Identification Methods two hybrid pooling approach, two hybrid, pull down, affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DASH_Duo1~DASH_Spc34
Common GO terms GO:0005737 - cytoplasm
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex
GO:0051301 - cell division
and 4 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024