Interactor 1: LAS1 (P36146)
Protein LAS1
Gene: LAS1

Interactor 2: GRC3 (Q07845)
Polynucleotide 5'-hydroxyl-kinase GRC3 (EC 2.7.1.-) (Protein GRC3)
Gene: GRC3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 25877921, 28652339, 26638174, 29440475, 32220933, 37968396, 38180340, 22083961, 23175604, unassigned1262
Identification Methods two hybrid, pull down, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CLP1_P~Las1
Common GO terms GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0090730 - Las1 complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 502
Sc

1 632
+ Hs
+ Sp

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Last updated: 15 Jul 2024